9 - 12Īs children mature, their intake of foods and fruit juices becomes more diversified. Ascorbic acid can significantly increase iron absorption, 6 - 9 while phytate and calcium may inhibit it. 5 In humans, iron absorption can be greatly influenced by the presence of enhancers and inhibitors of iron absorption in the rest of the diet. 3 Iron-deficiency anemia has been associated with lower scores on tests of mental and motor functioning in toddlers 4 and with worse school performance in adolescents. 2 In the United States, it is estimated that 8% of children aged 1 to 5 years are iron deficient. IRON-DEFICIENCY anemia remains the most prevalent nutritional deficiency in the world 1 and affects more than 2 billion people globally. 051).Ĭonclusions As children absorb iron well from a meal that includes either orange or apple juice, a preference for apple juice does not pose a concern with regard to the prospect of iron-deficiency anemia, which remains a significant health problem in the United States. 02) iron absorption from the meal that included orange juice tended to correlate with serum transferrin receptor concentration ( P =. Iron absorption from the meal that included apple juice was significantly correlated with serum ferritin concentration ( P =. Median iron absorption from the meal ingested with orange juice was 7.78% (9.80% ± 6.66% P =. Results Median iron absorption from the meal ingested with apple juice was 7.17% (mean ± SD, 9.48% ± 9.68%). Main Outcome Measures Iron absorption measured by established stable isotope methods. Intervention Identical meals served with orange juice and apple juice were given on consecutive days, in a balanced randomized design. Patients A total of 25 healthy children, 3 to 6 years of age, were recruited, of whom 21 (11 male and 10 female) completed the study. Setting Nutrition research institute in a major metropolitan medical center. Iron absorption was measured from red blood cell incorporation of the iron stable isotopes 14 days later. The meals were labeled with iron-57 on one day and iron-58 on the other. Objective To measure iron absorption in children from meals containing apple juice or orange juice so as to determine if iron absorption will be greater with orange juice because of its higher ascorbic acid content than apple juice, a noncitrus fruit juice that US children reportedly prefer.ĭesign On 2 successive days, children consumed identical meals that included apple juice on one day and orange juice on the other, in random order. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.
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